Endocrine Abstracts

Objective: To determine whether the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS) 4 nodules can be subcategorized by ultrasonography (US)-based stratification of malignancy risk, and to evaluate the diagnostic performance of the modified biopsy criterion based on the subcategorization of the K-TIRADS 4 category in a multicenter cohort.Materials and Methods: A total of 1,541 K-TIRADS 4 nodules (≥ 1 cm) with final diagnoses were include...

Introduction: Ethanol ablation (EA) of “persistent or recurrent” neck nodal metastases (NNM) in adult papillary thyroid carcinoma (APTC) patients was first introduced in 1993 to clinical endocrine oncologic practice (JCEM 2011;96: 2717). At Mayo Clinic we have been impressed by the efficacy of EA in controlling postoperative NNM in stage I APTC patients. We now describe the long-term outcome results of EA in controlling recurrent NNM in 41 patients consecutively mana...

Background: In November 2017, a nurse-led Adrenal Incidentaloma (AI) clinic was launched at the University Hospital of Wales (UHW), Cardiff, based upon the 2016 European Society of Endocrinology AI management guidelines.Objectives: To evaluate the effectiveness of a nurse-led clinic in managing AI patients at UHW.Methods: Retrospective analysis of electronic records of patients see...

Introduction: Hybrid closed-loop system (HCS) in Type 1 diabetes (T1D) management uses an automated algorithm to adjust basal insulin and administer correction doses to maintain glucose homeostasis. We have more children with HbA1c <58 mmol/mol. We aim to investigate if HCS contributed to this improvement.Methods: We identified TID children who started on HCS in our hospital from the year 2019–2023. Our HCS are ...

Red blood cell (RBC) deformability is an ability of RBC to change shape under stress, and it has been known to be decreased in diabetes. However, the role of RBC deformability is not determined in type 2 diabetes (T2D) yet. We attempted to clarify whether RBC deformability is related with diabetic complications. This was a cross-sectional study, and 452 T2D patients were enrolled. RBC deformability was measured by using a microfluidic ektacytometer, Rheoscan-D (Rheo-Meditech, ...

Parathyroid carcinoma, a rare endocrine malignancy, accounting for only 1–2% of patients with primary hyperparathyroidism (HPT). In addition, a few case have been reported coexistence of parathyroid carcinoma and papillary thyroid cancer. Here, we present a case of recurred parathyroid cancer with multiple lymph node metastasis. A 57-year-old women was presented with high serum calcium level (14.4 mg/dl) in medical check-up. Hyperparathyroidism was considered to be the re...

Background: Gas-forming pyogenic liver abscess is an uncommon, life-threatening infection that is usually found in poorly-controlled diabetic patients. Here, we experienced a case of gas-forming pyogenic liver abscess in diabetes caused by Klebsiella pneumoniae.Clinical case: A 77-year-old man with 25-year history of diabetes was admitted due to fever for 2 days. On the physical examination, right upper quadrant tenderness of the abdomen was present. Ini...

Introduction: Panhypopituitarism is a known but rare presentation of lymphoproliferative disease. We describe a patient with newly diagnosed advanced diffuse large B-cell lymphoma who presented with anterior hypopituitarism and concomitant adrenal gland involvement.Case report: A 72 year-old Chinese woman presented with a few weeks’ duration of lethargy, weight loss and functional decline. A hormonal screen done at admission suggested central hypoth...

Introduction: Hypogonadism is known to persist after treatment of hyperprolactinemia, necessitating androgen therapy in young male patients. Aromatisation of testosterone to estradiol can result in tumor expansion. We report a patient with persistent hypogonadism post treatment of macroprolactinoma and discuss challenges involved in the management.Case report: A 51-year-old gentleman was admitted for streptococcal meningitis. Brain imaging revealed a pit...

Introduction: Male hypogonadism secondary to AIDS is common and may present with non specific symptoms. Patients may self-diagnose hypogonadism and seek unauthorised androgen therapy. We report a male patient who developed polycythemia after receiving unauthorised sources of androgen therapy.Case report: A 42 years old man with AIDS diagnosed 10 years ago has repeatedly refused antiretroviral therapy. His most recent CD4 count was 314 cells/μl. His ...